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Drugmakers have brought almost 450 orphan drugs to market and collected rich incentives by doing so. But nearly a third of the medicines aren't new or were repurposed many times for financial gain.

Women often bear a heavier burden at times of crisis. Yet they draw on their inner strength to survive — and thrive. NPR photographed and interviewed 19 women over 3 weeks. Here are their stories.

Russia launched a major air attack early Thursday on Kyiv that included a rare strike on the city center, killing at least 21 people, wounding 48 and damaging European diplomatic offices.

Six months after electing a diverse wave of women to Congress, "electability"-minded Democrats fear the country isn't ready for a woman, person of color or LGBTQ presidential candidate.

Lightfoot is the city's first black female and openly gay mayor. After her swearing in, she laid out a plan to make Chicago "a city that families want to move to, not run away from."

The explosion in online holiday shopping means billions of packages need to be delivered — and companies like UPS, FedEx and Amazon are under more pressure than ever.

America's lobbying against the brand has had limited success. Many countries in Europe, Africa, the Americas and the Middle East are continuing their 5G rollout with at least some Huawei equipment.

Emails and interviews detail the extent to which the National Rifle Association helped two of Moscow's agents ahead of the election, Senate Finance Committee Democrats say.

If a Democrat wins an Ohio special election, it would be the latest sign of alarm for Republicans ahead of November's midterm election. Progressives hope for more upset wins Tuesday night.

You can often find ecologist Nalini Nadkarni up in trees. She studies this unexplored ecosystem of the rain forest — the canopy. It's the world above the forest floor, all the way to the treetops.