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Horseshoe crab blood is used to test vaccines around the world. But while Europe has approved a synthetic alternative, biomedical labs are bleeding more crabs from the Atlantic coast.

Pointing to an "unprecedented failure" at the top levels of Penn State leadership, the NCAA announced wide-ranging sanctions against the football program. NPR sports correspondent Mike Pesca talks about public reaction and what it could mean for the future of Penn State football.

Rap pioneer Joseph Simmons, also known as 'Run' of Run DMC, had a successful music career spanning more than three decades. For Tell Me More's 'Wisdom Watch' series, host Michel Martin talks with Rev. Run about his evolution from rapper to preacher.

After conviction, noncitizens face deportation in a second system of justice that has different rules and fewer protections. NPR followed one man — and his family — through the process.

The country is rich in water resources. Yet many people in the city of Santa Marta struggle to get enough to meet daily needs. They improvise, strategize — and rely on a tangle of 1-inch pipes.

Sheriff Jack Campbell has refused calls to resign following the death of Sonya Massey.

Vaccination campaigns have erased polio in almost every country in the world, but the disease persists in Afghanistan, Pakistan, and Nigeria. Obstacles in each country, including religious extremism, difficult terrain and transient populations, make eradication efforts difficult.

On Christmas Eve 2004, Urgent Envoy disappeared from his stable in the middle of the night. He had finished his only ever race in last place, but that didn't matter to the trainer who took him.

One hundred years ago this week, the radio barn dance that came to be known as the Grand Ole Opry was first broadcast from Nashville. Being part of the show still matters to country artists today.

Another year, another glitter-filled spectacle known as the Eurovision Song Contest. The Grand Final airs Saturday at 3:00 p.m. ET on Peacock in the United States.