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Seven astronauts died when the Space Shuttle Columbia disintegrated upon reentry on Feb. 1, 2003. NASA Deputy Administrator Pam Melroy looks back on the tragedy and how it shaped the agency.

Opponents of Myanmar's military rule heeded a call on Wednesday by organizers to stay home in a "silent strike" as the prospects for peace in the country seem dim 2 years after the army seized power.

Close to 40% of surveyed Americans, a record high, put off medical care last year because of finances. Americans are delaying or skipping doctor's visits, dental and vision care, and medications.

China has put the finishing touches on a sweeping leadership reshuffle that has been years in the making and puts trusted allies of leader Xi Jinping in key spots throughout the administration.

In intense courtroom moment, government’s star witness accused of saving his own skin

Ten people have been charged with murder in Otieno's death at a Virginia psychiatric hospital earlier this month. Caroline Ouko and attorney Ben Crump reflect on his life and what happens next.

The House tax plan differs significantly from the version being sculpted in the Senate. Both plans seem to agree that a big corporate tax cut is needed. The president wants a tax measure by Christmas.

On the opening day of her confirmation hearings, Supreme Court nominee Elena Kagan vowed to serve with a "commitment to evenhandedness, principle and restraint." She said the court must also "recognize the limits on itself and respect the choices made by the American people."

Truss became prime minister on Tuesday and immediately confronted the enormous task ahead of her amid increasing pressure to curb soaring prices, ease labor unrest and fix the health care system.

Grueling, unpredictable schedules are among the issues railroad workers are threatening to strike over. As a potential shutdown looms, here's a look at what the potential ramifications could be.